bruceine B

CAS No. 25514-29-8

bruceine B( —— )

Catalog No. M20422 CAS No. 25514-29-8

Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    bruceine B
  • Note
    Research use only, not for human use.
  • Brief Description
    Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.
  • Description
    Bruceine B a potent inhibitor of leukocyte-endothelial cell adhesion may have anti-inflammatory activity it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated HUVEC.
  • In Vitro
    Bruceine B exhibits an IC50 of 10 nM for antimalarial activity.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    TNF
  • Recptor
    TNF-α
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    25514-29-8
  • Formula Weight
    480.5
  • Molecular Formula
    C23H28O11
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [H][C@]12[C@@H](OC(C)=O)C(=O)O[C@]3([H])C[C@@]4([H])C(C)=C(O)C(=O)C[C@]4(C)[C@@]4([H])[C@@H](O)[C@H](O)[C@]1(OC[C@@]234)C(=O)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Utoguchi N Nakata T Cheng H H et al. Bruceine B A Potent Inhibitor of Leukocyte-Endothelial Cell Adhesion[J]. Inflammation 1997 21(2):223-233.
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